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NCT Number: NCT07000032

The Swallowing Function of Oral Cancer Surgery

This study enrolled patients who underwent oral cancer resection. Swallowing function, muscle status, and nutritional status were assessed before treatment, one month after treatment, and between three months to one year post-treatment.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

Dysphagia is a common and debilitating symptom among patients who undergo oral cancer resection with reconstruction followed by adjuvant radiotherapy. During the course of the disease, approximately 20% to 98% of patients experience swallowing difficulties. This is primarily caused by tumor destruction, postoperative sequelae from surgical resection, and the adverse effects of radiotherapy and chemotherapy. The use of chemotherapy or radiotherapy-particularly when combined-increases the incidence of complications such as oropharyngeal mucositis, odynophagia, dysgeusia, xerostomia, nausea, vomiting, and fatigue. These complications may lead to dehydration and significant weight loss, which in turn negatively impact nutritional status, functional ability, and quality of life.

This study enrolled patients who underwent oral cancer surgery. Swallowing function, muscle status, and nutritional status were assessed before treatment, one month after treatment, and between three months to one year post-treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients undergoing oral cancer

Exclusion criteria

  • patients unable to unable to cooperate with the examination

Treatment and study plan

No Intervention: Observational Cohort

Other

This is an observational cohort

Primary outcomes

  1. bolus presence time

    Time frame: one year after surgery

    The opening of hypopharynx

Study contacts

Contact information is provided by the study sponsor or research team.

Chih-Jun Lai, MD, PhD

CONTACT

[email protected]

+886-972652086

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

A Longitudinal Study on Dysphagia and Associated Nutritional Complications Following Oral Cancer Surgery

Important dates

Study start
2025
Primary completion
2030
Study completion
2032
First posted
May 31, 2025
Registry last updated
May 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.