The Surveillance Clinical Study of Rickettsiosis

This is an observational study with no intervention by the Sponsor or CRO in routine treatment or diagnostic process. Patient treatment strategy is not influenced by the study protocol or by the physician's intention to include the patient in the study; instead, is based on current standards of medical care for patients with rickettsioses.

The researcher (practicing physician) are being required to obtain written informed consent form (ICF) from each patient prior to inclusion. Biological sample collection are carried out using residual samples from standard diagnostics of patients who have signed an informed consent agreement. The researcher (practicing physician) start complete an individual case report form (CRF) for each patient who signed informed consent and whose biological samples have been collected.

Prior to the commencement of the study, the sponsor obtained approval from the ethics committee to conduct the study.

Inclusion criteria

To be included in the study, the subject must meet all the following criteria:

• Written informed consent by the subject (or their legal representative) to participate in the study;
• Men and women of any age, including children, who:

have sought medical care (outpatient or inpatient) with suspected or diagnosed rickettsiosis; or have sought medical care (inpatient) with a history of tick bites and elevated body temperature (at least 37.2 °C lasting at least 48 hours).

Exclusion criteria

• Inability or unwillingness of the subject (or their legal representative) to participate in the study