Faculty of Medicine, Chulalongkorn University
Bangkok, 10330, Thailand
Completed
NCT Number: NCT00853476
The Standard Concentration of Morphine as a Positive Control for Intradermal Skin Test
This study aims to compare skin reactivity results between morphine and histamine as a positive control agents in intradermal skin test.
Completed
Looking for future studies?
Notify MeKey information
Conditions
Age range
18 year–60 year
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
Histamine hydrochloride and different concentrations of morphine sulfate will be intradermally injected and wheal diameter size will be comparatively measured between 15-30 minutes' time points after the test.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- age 18-60 years old
Exclusion criteria
- immunodeficiency state
- cancer
- severe skin diseases
- severe medical illnesses
- malnutrition
- uncontrolled asthma
- pregnancy
- received oral or systemic corticosteroid within 1 month before this study
- receiving immunosuppressive agents
- taken antihistamine within 3 days before this study
- taking beta-blocker
- previous history of immunotherapy
- have hypersensitivity reaction to morphine/opiates
Treatment and study plan
Primary outcomes
-
Wheal diameter from morphine skin test at different concentrations compared to standard histamine between 15-30 minutes after skin test
Time frame: 30 minutes
Secondary outcomes
-
Side effects
Time frame: 24 hours
Sponsors and collaborators
Lead sponsor
Chulalongkorn University
Other
Registry information
Important dates
- Study start
- 2009
- Primary completion
- 2009
- Study completion
- 2009
- First posted
- Mar 2, 2009
- Registry last updated
- Feb 18, 2011
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.