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OpenTrials
Completed

NCT Number: NCT00927303

The Spectralis-Cirrus Study

Retinal thickness measurement is one of the most important examinations in the follow up of exudative age-related macular degeneration. Prior studies have shown that there are a series of algorithm line failures in OCT examinations. This study is conducted to compare the quality of the examinations of to different spectral domain OCT machines concerning the positioning of algorithm lines. Furthermore the reproducibility of the examinations id tested, both machines provide different techniques to guarantee that in repeated examinations the same location is examined.

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Key information

Conditions

Exudative Age Related Macular Degeneration

Age range

50 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery

Vienna, State of Vienna, 1030, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Exudative age related macular degeneration

Exclusion criteria

  • Macular pathologies other than age related macular degeneration (diabetic maculopathy, macular pucker, macular hole,
  • Visualization of the macula not possible (dens cataract, vitreous haemorrhage)
  • Not consented patients

Treatment and study plan

Cirrus-Spectralis

Device

512x128 cúbe program of Cirrus OCT first retinal volume 121 line of Spectralis OCT thereafter

Spectralis-Cirrus

Device

retinal volume program 121 lines Spectralis OCT first 512x128 program Cirrus OCT thereafter

Primary outcomes

  1. Number of examinations with correctly set threshold algorithm lines

    Time frame: 1 day

Secondary outcomes

  1. Differences of mean retinal thickness in the central region

    Time frame: 1 day

  2. Differences of retinal volume

    Time frame: 1 day

  3. Distance acuity

    Time frame: 1 day

  4. Age

    Time frame: 1 day

  5. Classification of the lesion

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

Other

Registry information

Official study title

Comparison of Quality and Reproducibility of Retinal Thickness Measurements in Two Spectral Domain OCT- Machines

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Jun 24, 2009
Registry last updated
Jun 9, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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