Lichtenstein operation with a heavy-weight mesh
ProcedureBard flat mesh, polypropylene, 7,5 x 15 cm, 90 g/m2
NCT Number: NCT00451893
The trial compares the postoperative complain, pain, quality of life after the implantation of a heavy-weight alternative light-weight mesh, by randomly allocating patients with inguinal hernia disease to two groups of surgeons, each group being trained to operate with one of the above mentioned meshes.
Hypothesis: There is less postoperative pain after the implantation of a light-weight mesh.
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Notify Me25 year and older
Male
Interventional
Not applicable
Department of Surgical and Perioperativ Sciences, Umeå University Hospital, Umeå, Sweden
The implantation of mesh in the operation of inguinal hernia has resulted in a continuously diminishing frequency of reoperations. Randomized controlled trials indicate that hernia repair with an open mesh technique has a shorter learning curve, is cheaper and may give less recurrences than laparoscopic hernia repair in general surgical practice. Furthermore, local anesthesia has significant advantages for both the patient and the health related economy compared to general anesthesia and regional anesthesia. The experience of the last decade within the field of groin hernia surgery has focused interest on quality of life and postoperative pain (especially chronic pain). Chronic pain is defined as pain that remains 3 months after the operation. Recent studies indicate that one third of all patients operated on for inguinal hernia have some degree of chronic pain and that 4-6 % of patients have pain interfering with daily activities one year after surgery.
In the present study a heavy-weight polypropylene mesh will be compared with a light-weight partly absorbable mesh. In an expertise-based randomized control trial patients will be randomly allocated to two groups of surgeons, each group well trained to use one of the two meshes.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Bard flat mesh, polypropylene, 7,5 x 15 cm, 90 g/m2
Johnson&Johnson Ultrapro, polypropylene/poliglecaprone, 10 x 15 cm, 28 g/m2
Time frame: Four months after the operation.
McCarthy Visual analog scale (0-150 mm) for postoperative pain. Higher value indicates more pain.
Time frame: One year after the operation.
McCarthy Visual analog scale (0-150 mm) for postoperative pain. Higher value indicates more pain.
Time frame: One year after the operation.
The EQ-5D index is a summary measure based on a questionnaire with five domains, each comprising three levels.
Time frame: 10 years
Inguinal Pain Questionnaire for assessing impact on daily activities. The short form of Inguinal Pain Questionnaire has 7 grades (1-7). Increasing grade means more pain. Grade 1 represents no pain.
Time frame: 2 days after the operation
The EQ-5D index is a summary measure based on a questionnaire with five domains, each comprising three levels.
Time frame: Seven days after the operation.
The EQ-5D index is a summary measure based on a questionnaire with five domains, each comprising three levels.
Time frame: Eleven days after the operation.
The EQ-5D index is a summary measure based on a questionnaire with five domains, each comprising three levels.
Time frame: Four months after the operation
The EQ-5D index is a summary measure based on a questionnaire with five domains, each comprising three levels.
Time frame: Within one year after the operation.
Description and frequency of postoperative complications
Time frame: Within one year after the operation.
Recurrences of inguinal hernia
Time frame: Within one year after the operation.
Total health-care costs
Time frame: Within one year after the operation.
Post operative sick leave
Umeå University
Other
An Expertise-based Multicentre Randomized Controlled Trial Comparing a Heavy-weight and a Light-weight Mesh in the Operation of Inguinal Hernia
Acronym: LJUNO
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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