NCT Number: NCT01239524
The Significance of Latissimus Dorsi Flap Innervation in Delayed Breast Reconstruction
Breast reconstruction with a pedicled myocutaneous latissimus dorsi (LD) flap is a widely used reconstruction method. It is controversial if surgical denervation by transecting the thoracodorsal nerve should be performed or not. It is assumed that after denervation the latissimus dorsi muscle will significantly atrophy and lose volume. On the other hand discomforting signs and symptoms from muscle contraction are believed to be prevented if flap is denervated. The aim of the study was prospectively evaluate the influence of LD-flap innervation on the functional and aesthetic outcome of delayed breast reconstruction, and to compare the change in muscle structure in breast MRI and histopathology.
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Notify MeKey information
Age range
20 year–70 year
Sex eligibility
Female
Study type
Interventional
Phase
Phase 3
Who can participate
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- delayed LD-flap breast reconstruction, no recurrent disease observed
Exclusion criteria
- recurrent cancer, partial resection of the breast
Treatment and study plan
Sponsors and collaborators
Lead sponsor
Tampere University Hospital
Other
Registry information
Important dates
- First posted
- Nov 11, 2010
- Registry last updated
- Nov 11, 2010
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