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OpenTrials
Completed

NCT Number: NCT01239524

The Significance of Latissimus Dorsi Flap Innervation in Delayed Breast Reconstruction

Breast reconstruction with a pedicled myocutaneous latissimus dorsi (LD) flap is a widely used reconstruction method. It is controversial if surgical denervation by transecting the thoracodorsal nerve should be performed or not. It is assumed that after denervation the latissimus dorsi muscle will significantly atrophy and lose volume. On the other hand discomforting signs and symptoms from muscle contraction are believed to be prevented if flap is denervated. The aim of the study was prospectively evaluate the influence of LD-flap innervation on the functional and aesthetic outcome of delayed breast reconstruction, and to compare the change in muscle structure in breast MRI and histopathology.

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Key information

Age range

20 year–70 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • delayed LD-flap breast reconstruction, no recurrent disease observed

Exclusion criteria

  • recurrent cancer, partial resection of the breast

Treatment and study plan

denervation of thoracodorsal nerve or saving the nerve

Procedure

Sponsors and collaborators

Lead sponsor

Tampere University Hospital

Other

Registry information

Important dates

First posted
Nov 11, 2010
Registry last updated
Nov 11, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.