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NCT Number: NCT06918353

The Severity Assessment Model for AECOPD With Combination of Disease and Syndrome

The establishment of the AECOPD severity assessment model can quickly and accurately evaluate the condition, which is of great significance for standardizing diagnosis and treatment, improving efficacy, and improving prognosis. At the same time, it can provide ideas and methods for the research of disease assessment models in related fields.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

Zhengzhou, Henan, 450000, China

Location contact

Hailong H Zhang, doctor

CONTACT

[email protected]

+86-0371-66248624

About this study

Accurate assessment of the condition is the prerequisite and basis for standardized clinical treatment. Traditional Chinese medicine has shown good efficacy and advantages in treating AECOPD, but currently there is no ideal standard for judging the severity, nor is there an accurate, practical, and TCM specific disease assessment tool. Therefore, this project integrates multidimensional variables of traditional Chinese and Western medicine, and intends to conduct research on the construction of a disease syndrome combined AECOPD disease assessment model through literature review, expert consultation, clinical investigation, and machine learning algorithms, and establish preliminary grading standards for the severity of AECOPD disease. Ultimately, it provides ideas and methods for the rapid and accurate assessment of AECOPD, standardized diagnosis and treatment, improved efficacy, improved prognosis, and research on disease assessment models in related fields.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Meets AECOPD diagnostic criteria.
  • Voluntarily participate in the research and sign the consent form

Exclusion criteria

  • Individuals with severe mental disorders and cognitive impairments who are unable to communicate normally

Treatment and study plan

Diagnosis and Severity Grading of AECOPD Disease

Diagnostic Test

Diagnosis and severity grading of AECOPD disease, as well as assessment of traditional Chinese medicine syndromes

Primary outcomes

  1. Clinical Investigation Questionnaire on Influencing Factors of the Severity of AECOPD

    Time frame: 24 hours

    The influencing factors of the severity of AECOPD were evaluated through clinical investigation questionnaires.

    Questionnaire Title: Clinical Investigation Questionnaire on Influencing Factors of AECOPD Severity.

    The questionnaire adopts the scoring method, which is divided into "very unimportant", "not important", "average", "important" and "very important", and the corresponding values are assigned as 1, 2, 3, 4 and 5 respectively.The higher the score is, the more significant the result is.

Study contacts

Contact information is provided by the study sponsor or research team.

Hailong H Zhang, doctor

CONTACT

[email protected]

+86-0371-66248624

Sponsors and collaborators

Lead sponsor

Henan University of Traditional Chinese Medicine

Other

Collaborators

  • Henan Provincial People's Hospital
  • Jiangsu province hospital of TCM
  • Qingdao Traditional Chinese Medicine Hospital(Qingdao Hiser Hospital)
  • Shangcai County Traditional Chinese Medicine Hospital
  • The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
  • Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
  • Xiangyang Hospital of Traditional Chinese Medicine
  • Yanshi People's Hospital of Luoyang City

Registry information

Official study title

Construction and Evaluation of the Severity Assessment Model for AECOPD With Combination of Disease and Syndrome Based on Machine Learning

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Apr 9, 2025
Registry last updated
Apr 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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