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NCT Number: NCT02049658

The Sensitivity and Specificity of Sniff Dog as a Tool in Diagnosing the Suspected Tumor Patients

Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in identifying cancer patients in the high risk population or suspected patients. Trained dogs will sniff serum from participants who are suspected to suffer from tumor by their physicians and not yet but will be diagnosed by pathological examination.The results will be compared with the outcome of the pathological examination.

Recruiting

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Key information

Conditions

Neoplasia Neoplasms

Age range

1 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy volunteers who have been examined by the currently used procedures and find to be without tumors.
  • Patients in the breast surgery, thoracic surgery, gynecological and neurosurgery departments with lesions with characteristics of tumors

Exclusion criteria

  • Patients who have had pathological results

Treatment and study plan

Primary outcomes

  1. sensitivity and specificity of the sniff dogs as a tool in diagnosing tumors

    Time frame: 12 months

    The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination as non-cancer subjects.

Secondary outcomes

  1. behavior patterns of the sniff dogs to different diseases

    Time frame: 12 months

    The behavior (lying before the tank for positive, neglecting the tanks) of the dog will be recorded and compared with the results of the pathological examination.

Other outcomes

  1. the substances used for identifying tumors by the sniff dogs

    Time frame: 12 months

    GCMS etc will be used to compare the volatile compounds between the sera from cancers patients and the from non-cancer subjects, the suspected VOCs will be tested by the dog for conformation.

Study contacts

Contact information is provided by the study sponsor or research team.

Chang-Qing Gao, MD PhD

CONTACT

[email protected]

86 188 7486 9488

Ya-Qin Wang, MD PhD

CONTACT

[email protected]

86 15274810930

Sponsors and collaborators

Lead sponsor

Chang-Qing Gao

Other

Registry information

Important dates

Study start
2014
Primary completion
2025
Study completion
2026
First posted
Jan 30, 2014
Registry last updated
Feb 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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