The Roles of Tissue Factor in Malignant Gliomas

To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

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Key information

Conditions

Venous Thromboembolism Brain Diseases Brain Neoplasms Brain Tumors Cardiovascular Diseases Central Nervous System Diseases Central Nervous System Neoplasms Disease Attributes Disease Progression Embolism and Thrombosis Glioma Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue Neoplasms, Neuroepithelial Nervous System Diseases Nervous System Neoplasms Neuroectodermal Tumors Pathologic Processes Pathological Conditions, Signs and Symptoms Thromboembolism Thrombosis Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Cross Cancer Institute, Edmonton, Alberta, Canada

About this study

To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

participation in PRODIGE
adult patients
newly diagnosed, biopsy-confirmed grade III/IV malignant gliomas
undergone craniotomy or stereotactic biopsy > 2 days and < 4 weeks before

Exclusion criteria

have known hereditary thrombophilia
are receiving experimental antiangiogenic therapy

Sponsors and collaborators

Lead sponsor

Ontario Clinical Oncology Group (OCOG)

Other

Collaborators

Ontario Cancer Research Network

Registry information

Important dates

Study start: 2004
Study completion: 2006
First posted: Sep 20, 2005
Registry last updated: Apr 6, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed