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Recruiting

NCT Number: NCT06607887

The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.

Recruiting

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Key information

Conditions

Infection Wound Antibiotic Resistant Infection Infections Wound Infection

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Minia University Hospital

Minya, Egypt

Location status: Recruiting

Location contact

asmaa Elsayed, Ph.D.

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy.

Exclusion criteria

  • patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.

Treatment and study plan

IV antibiotic

Drug

Parenteral prophylactic antibiotics (cefazolin), 1st dose at the time of induction of anesthesia, 2nd dose after 12hs from the surgery.

Oral antibiotic

Drug

Parenteral prophylactic antibiotic (cefazolin), dose at the time of induction of anesthesia and then oral antibiotic for five days postoperative.

Primary outcomes

  1. Surgical site infection

    Time frame: 4 weeks

    DSSI = deep surgical site infection; SSSI = superficial surgical site infection.

Secondary outcomes

  1. Fever

    Time frame: 4 weeks

  2. Length of the hospital stay

    Time frame: 4 weeks

  3. Hematoma and Seroma formation

    Time frame: 4 weeks

Study contacts

Contact information is provided by the study sponsor or research team.

Asmaa A Elsayed

CONTACT

[email protected]

01095727201

Sponsors and collaborators

Lead sponsor

Minia University Hospital

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Sep 23, 2024
Registry last updated
Sep 23, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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