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Completed

NCT Number: NCT02740101

The Role of Oxytocin in Modulating the Effects of Social Feedback on Achieving Personal Goals

To examine potential differential effects of receiving various social feedback on achieving personal goals,and whether oxytocin would modulate these effects.

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Key information

Conditions

Healthy

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Early Phase 1

Primary location

school of life science and technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, 610054, China

About this study

In the present study, 62 healthy male participants participated in the double-blind, placebo-controlled experiment. Investigators aimed to test the idea that whether oxytocin would modulate subjective responses during receiving various social reward and social punishment about the future outcomes of pursuing personal goals.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion criteria

  • Taking oral contraceptives;
  • No history of head injury and medical or psychiatric illness.

Treatment and study plan

oxytocin treatment

Drug

intranasal administration of oxytocin (40 IU)

placebo treatment

Drug

intranasal administration of placebo (40 IU)

Primary outcomes

  1. Rating of Encouragement after receiving specific social feedback

    Time frame: one hour

    There're 96 different social feedback totally for four goals which were divided into four runs consisting of 24 different feedback separately for each goal video.Therefore,subjects were instructed to complete the encouragement rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum encouragement while nine refers to maximum encouragement.

Secondary outcomes

  1. Rating of Likeability after receiving specific social feedback

    Time frame: one hour

    There're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Therefore,subjects were instructed to complete the likeability rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum likeability while nine refers to maximum likeability.

Other outcomes

  1. Rating of Confidence after receiving a series of social feedback

    Time frame: one hour

    There're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Furthermore, these 24 feedback were categorized into three types which include 8 feedback separately.Therefore,subjects were instructed to complete the confidence rating after receiving these 8 feedback together. To measure the rating, the investigators used the 9-point likert scale in which one refers to the minimum confidence while nine refers to maximum confidence.

Sponsors and collaborators

Lead sponsor

University of Electronic Science and Technology of China

Other

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Apr 15, 2016
Registry last updated
Mar 6, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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