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NCT Number: NCT01178190

The Role of Narrow Band Imaging Videobronchoscopy in Lung Cancer

Narrow band imaging (NBI) videobronchoscopy is an optical technique in which filtered light enhances superficial neoplasm based on their neoangiogenic pattern. The objectives of this study investigate its better diagnostic yield in the assessment of lung cancer than conventional flexible bronchoscopy.

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Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

ChangMin, Choi

Seoul, South Korea

About this study

Inspection with high resolution endoscopy was followed by NBI. Detected lesions were biopsied. applied the system of shibuya et al. to analyze and classify vascular patterns by NBI into four categories (spiral and screw pattern, dotted pattern, tortuous pattern, avascular pattern) compared with the known diagnostic yield of conventional white light bronchoscopy, An equivalent or superior result will also significantly impact on patient care This technology could aid not only early-stage lung cancer diagnosis but also more accurate local staging of lung cancer.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • endobronchial lesion on chest CT

Exclusion criteria

  • Age < 18 years old
  • Inability to consent for the study
  • Inability to tolerate bronchoscopy
  • Active pulmonary infection (bronchitis, pneumonia)
  • ST elevation or depression on ECG
  • Prothrombin time prolongation(<70%)
  • platelet <10,000

Treatment and study plan

Primary outcomes

  1. accuracy of NBI videobronchoscopic biopsy

    Time frame: 10-11 months

    Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for lung cancer.

Secondary outcomes

  1. early cancer lesion detection rate using Shibuya descriptors

    Time frame: 10-11 months

    Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for early lung cancer.

Sponsors and collaborators

Lead sponsor

Asan Medical Center

Other

Registry information

Official study title

The Diagnostic Yield of Narrow Band Imaging Videobronchoscopy in Lung Cancer

Acronym: NBI

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Aug 10, 2010
Registry last updated
Aug 10, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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