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OpenTrials
Completed

NCT Number: NCT07416643

The Role of Incorporating Acacia Gum in Foods on Glucose Homeostasis in Healthy Humans

Abnormal postprandial blood glucose (PPG) is considered as a strong predictor for developing metabolic diseases worldwide. Nowadays, little understanding is available on how a carbohydrate-rich food matrix and the starch structures within interact with the gastrointestinal tract to help in controlling PPG. In this investigation, the use Acacia gum enriched flour will be used to explore the effect of adding the gum as food supplement on PPG in healthy humans.

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Key information

Conditions

Health Adult Subjects

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

King Fahd Medical Research center

Jeddah, Saudi Arabia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female self-reported healthy volunteers (aged 18 to 40 years)
  • Normal to overweight individuals (body mass index (BMI) 18.5-30 kg/m2) o BMI is equal to body weight (kg) divided by height squared (m2)

Exclusion criteria

  • History of substance abuse
  • Excessive alcohol intake
  • Pregnancy
  • Diabetes
  • Cardiovascular disease
  • Cancer
  • Any gastrointestinal disease e.g. irritable bowel syndrome or inflammatory bowel disease
  • Kidney disease
  • Liver disease
  • Pancreatitis
  • Use of medications likely to interfere with energy metabolism, appetite regulation and hormonal balance, including: anti-inflammatory drugs or steroids, antibiotics, androgens, phenytoin, erythromycin or thyroid hormones.

Treatment and study plan

incorporating acacia gum flour into commonly consume foods

Dietary Supplement

incorporating acacia gum flour into commonly consume foods

Primary outcomes

  1. postprandial blood glucose

    Time frame: 0 minutes and postprandial timepoints: 15 minutes, 30 minutes, 60 minutes,120 minutes,180 minutes

Sponsors and collaborators

Lead sponsor

King Abdulaziz University

Other

Registry information

Official study title

The Role of Incorporating Acacia Gum in Foods on Glucose Homeostasis in Healthy Humans: a Pilot Study

Acronym: AcaciaGlu

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Feb 18, 2026
Registry last updated
Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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