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OpenTrials
Completed

NCT Number: NCT02980939

The Role of Hydration on Exercise Performance - ODIN

During exercise in the heat, there is a need to replenish fluids in order to avoid dehydration and decrease the risk for heat illness. What drives this urge to drink is the thirst mechanism. Following ingestion of fluids, there is an inhibition of thirst before there is a replenishing of fluids. However, there is little scientific evidence of where thirst is inhibited, if this thirst inhibition is augmented by exercise and how thirst itself influence exercise performance. Further, during rehydration studies, it is very difficult to successfully blind a subject to their drinking/hydration protocol. Previous studies that have blinded a subject to their drinking have used various methods such as intravenous fluid administration and/or nasogastric tubes. Therefore, the purpose of this research is to examine the mechanistic roles thirst inhibition plays while exercising in the heat while undergoing intravenous fluid administration. Specific attention will be directed to the cardiovascular and thermoregulatory function of the individuals. All blood, cardiovascular, thermoregulatory, and perceptual measures are shown in the diagram below.

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Key information

Age range

18 year–45 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Arkansas - HPER

Fayetteville, Arkansas, 72701, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cycling Racing History category 3 or higher USA cycling certification
  • maximal oxygen uptake >55 ml/kg/min

Exclusion criteria

  • History of heat stroke
  • Renal, cardiovascular, metabolic diseases
  • Regular medication

Treatment and study plan

iv fluid infusion

Other

Intravenous isotonic saline infusion

Primary outcomes

  1. 5km - Cycling Time Trial

    Time frame: 2hour

    Time to completion 5 km cycling time trial in the heat

Secondary outcomes

  1. Rectal Temperature

    Time frame: 2hour

    Body core temperature at the end of the 5 km time trial

Sponsors and collaborators

Lead sponsor

University of Arkansas, Fayetteville

Other

Registry information

Acronym: ODIN

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Dec 2, 2016
Registry last updated
May 31, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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