The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation

The aim of this study is to evaluate the role of high-resolution computed tomography of the chest (HRCT) in the investigation of an outbreak of TB that developed in the South Korean army.

Completed

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Key information

Conditions

Tuberculosis Actinomycetales Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections Mycobacterium Infections

Sex eligibility

Male

Study type

Observational

About this study

Outbreak investigation including tuberculin skin test (TST), QuantiFERON® TB Gold In-Tube (QFT), and simple chest radiography (CXR) will be performed. For participants with any abnormal findings in these tests, HRCT will be carried out. Active pulmonary TB is diagnosed based on sputum studies or HRCT findings. In addition, participants with positive results both in TST and QTF will be treated as having a latent TB infection (LTBI). TST and QTF were repeated in participants with positive result in one of these tests. CXR will be repeated in all participants at 3 and 6 months of follow-up.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All soldiers who assigned to the military battery where a tuberculosis outbreak occurred

Exclusion criteria

Soldiers who could not complete study

Sponsors and collaborators

Lead sponsor

Armed Forces Capital Hospital, Republic of Korea

Other Gov

Registry information

Official study title

The Role of Addition of High Resolution-CT in Outbreak Investigation of Tuberculosis

Important dates

Study start: 2007
Primary completion: 2009
Study completion: 2009
First posted: Apr 29, 2009
Registry last updated: Sep 23, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed