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Completed

NCT Number: NCT03190772

The Role of Expectations in the Pharmacological Treatment of Depression - An Experimental Investigation

The study aimes at identifying whether positive expectations have an impact on the way depressive participants experience emotions in the form of sadness.

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Key information

Conditions

Major Depressive Episode

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Justus Liebig University Gießen, Giessen, Hesse, Germany

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • major depression (mild to moderate)
  • fluent in German language

Exclusion criteria

  • bipolar disorder, psychotic disorder, substance dependence
  • cardiovascular disease, severe kidney or liver disease, epilepsy
  • change of psychotropic medication intake within the last four weeks
  • allergic to capsaicin
  • allergic to sesame oil
  • students in medicine, pharmacy, or psychology in their third year or older
  • completed studies in medicine, pharmacy or psychology

Treatment and study plan

Placebo nasal spray

Other

The placebo nasal spray consists of sesame oil and does not contain any active drug.

Film sequence

Other

All groups watch the film sequence that is supposed to induce sadness.

Primary outcomes

  1. Sadness

    Time frame: Directly after watching the film sequence, no follow-up assessments

    Items of PANAS-X

Sponsors and collaborators

Lead sponsor

Philipps University Marburg

Other

Registry information

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 19, 2017
Registry last updated
Nov 7, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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