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NCT Number: NCT06164067

The Role of Cervical Consistency Index and Uterocervical Angles in Medical Termination

The main aim of the investigator study is the success of predictivity cervical consistency index (CCI), anterior uterocervical angle (aUCA) and posterior uterocervical angle (pUCA) in second trimester terminations.

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Key information

Conditions

Second Trimester Abortion Cervical Consistency Index Uterocervical Angle

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Nefise Nazlı YENIGUL

Bursa, 16110, Turkey (Türkiye)

About this study

This prospective clinical study includes 136 pregnant women with a diagnosis of in utero ex fetus who were hospitalized for medical termination in the gynecology service of Health Sciences University Bursa High Specialization Training and Research Hospital Gynecology and Obstetrics Clinic as a single center. The participants were divided into 2 groups as those whose treatment was completed in the first 24 hours (who were completely aborted and removed the fetal material and its attachments ) and those who aborted within 24-48 hours when additional cycles were needed. Furthermore who applied to additional treatment methods were recorded (cervical balloon, hysterotomy ) during these periods. In all pregnant women; characteristic features, abortion times, doses of misoprostol used, anterior- posterior uterocervical angle, cervical length, cervical consistency indexes and gestational weeks were saved.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • women who had a termination indication in the second trimester and had abortion or abortion in our hospital
  • women who have had a miscarriage or abortion with a normal vaginal route or hysterotomy

Exclusion criteria

  • multiple pregnancies
  • pregnant women with misoprostol-related allergies
  • scar pregnancies or heterotopic pregnancies
  • patients with a history of previous conization or cervical surgery,
  • patients with placental invasion anomaly

Treatment and study plan

abortus within 24 hours or 24-48 hours

Other

second trimester medical termination

Other names: misoprostol

Primary outcomes

  1. success of predictivity cervical consistency index, anterior uterocervical angle and posterior uterocervical angle

    Time frame: 6 months

    cervical consistency index (CCI), an ultrasound measurement that aims to estimate cervical softness by measuring the anteroposterior diameter of the uterine cervix before (AP) (millimeter) and at maximal compression (AP') with the vaginal ultrasound probe and calculating the ratio between the two measurements (AP'/AP × 100). Uterocervical angle (UCA) (degree):Transvaginal sonographic images showing technique of measurement of uterocervical angle. UCA was calculated as angle between two lines. The first line was drawn between internal (I) and external ostium (os) (E). The second line was drawn 3 cm parallel to the lower aspect of anterior inner uterine wall passing through the end of the first line at internal os. (in degrees)

Secondary outcomes

  1. compare the measured ultrasonographic values

    Time frame: 6 months

    compare the measured ultrasonographic values with the success of predictivity cervical length.( millimeter)

Sponsors and collaborators

Lead sponsor

Sanliurfa Mehmet Akif Inan Education and Research Hospital

Other

Registry information

Official study title

The Role of Cervical Consistency Index and Uterocervical Angles in Predicting Second Trimester Medical Termination

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Dec 11, 2023
Registry last updated
Dec 11, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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