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OpenTrials
Completed

NCT Number: NCT00006196

The Relationship Between Vitamin D, Fingernail Thickness and Bone Density

Vitamin D deficiency is common in the elderly and contributes to the increased incidence of falls, hip fracture and depression in this population. An unknown number of elderly have vitamin D resistance resulting in a functional vitamin D deficiency state. Because there are no simple procedures or blood tests that identify vitamin D resistance, its prevalence and contribution to disability in the elderly is unknown. Our inability to screen for this condition precludes our ability to initiate and monitor treatment.

Previous studies indicate that fingernail thickness correlates with vitamin D status and may therefore provide a simple cost effective procedure to not only identify patients with vitamin D deficiency but also, those with vitamin D resistance. This procedure may also provide a way to monitor an individual's response to treatment.

This study is designed to demonstrate the association between fingernail thickness and vitamin D status.

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Key information

Age range

25 year–75 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 1

Primary location

4488 Forest Park, Suite 201

St Louis, Missouri, 63108, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • females 25-75 years of age with no known bone disorders

Exclusion criteria

  • history of vertebral fractures or nonvertebral fractures without trauma
  • prescription medications for prevention of osteoporosis (including vitamin D other than multivitamin and estrogen)
  • history of malignancy other than basal cell or squamous cell cancer of the skin
  • use of steroids or anticonvulsants in the 6 months prior to enrollment

Treatment and study plan

Vitamin D

Drug

Sponsors and collaborators

Lead sponsor

National Center for Research Resources (NCRR)

Nih

Registry information

Important dates

First posted
Sep 8, 2000
Registry last updated
Jun 24, 2005

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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