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Completed

NCT Number: NCT04597814

The Relationship Between the Tumor Markers and Interstitial Lung Disease

The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.

This study was undertaken to investigate the source of these serum tumor markers.

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Key information

Conditions

the Relationship Between the Tumor Markers and Interstitial Lung Disease Patients

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, 520120, China

About this study

The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.

This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung.

The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1.Interstitial lung disease patients for lung transplantation

-

Exclusion criteria

  • tumor
  • Interstitial lung disease patients could not be performed by lung transplantation

Treatment and study plan

No intervention

Other

No Intervention

Primary outcomes

  1. serum levels of carcinoembryonic antigen (CEA)

    Time frame: 6months

    serum levels of carcinoembryonic antigen (CEA)

  2. serum levels of carbohydrate antigen 19-9 (CA19-9)

    Time frame: 6months

    serum levels of carbohydrate antigen 19-9 (CA19-9)

  3. serum levels of carbohydrate antigen 125(CA125)

    Time frame: 6months

    serum levels of carbohydrate antigen 125(CA125)

  4. The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)

    Time frame: 1 week

    The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)

  5. The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)

    Time frame: 1 week

    The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)

  6. The alveolar lavage fluid levels of carbohydrate antigen 125

    Time frame: 1 week

    The alveolar lavage fluid levels of carbohydrate antigen 125

  7. The lung tissue levels of carcinoembryonic antigen (CEA)

    Time frame: 1 week

    The lung tissue levels of carcinoembryonic antigen (CEA)

  8. The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)

    Time frame: 1 week

    The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)

  9. The lung tissue levels of carbohydrate antigen 125

    Time frame: 1 week

    The lung tissue levels of carbohydrate antigen 125

Sponsors and collaborators

Lead sponsor

The First Affiliated Hospital of Guangzhou Medical University

Other

Registry information

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Oct 22, 2020
Registry last updated
Oct 23, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.