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Completed

NCT Number: NCT02747966

The Relationship Between the Flow of Arteriovenous Fistula and Cardiac Function in Haemodialysis Patients

A prospective longitudinal surveillance for a period of 2 months. Sample - identify suitable Chronic Kidney Disease (CKD) patients who undergo HD with functioning AVF. Participants at various age range and both sexes are recruited to observe their access flow, access recirculation and cardiac function and assess their relationship.

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Key information

Conditions

Complication of Hemodialysis

Age range

16 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The 1st Affiliated Hospital, Sun Yet-sen University

Guangzhou, Guangdong, 510080, China

About this study

All patients recruited who met the inclusion criteria were investigated access flow, access recirculation and cardiac function(including cardiac output,cardiac index,central blood volume,et al).Measurement time is the beginning of HD session (first 30min to 1 hr),Middle of HD session (optional),and the end of the HD session (1hr to 30 min prior to end of session). The follow-up duration is 6 months and 12 months.Repeat the assessment at the above time points.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergo HD with native AVF
  • AF of AVF between 300ml/min and 1800ml/min

Exclusion criteria

  • Patients whose AVF developed Access Recirculation (AR) which cannot be resolved at the time of measurement
  • Patients developed access or systemic infection during the study period

Treatment and study plan

Primary outcomes

  1. to access the chang of the fistula blood flow in HD patients using Ultrasound Dilution method

    Time frame: Change of the fistula blood flow from baseline to 6 months

Secondary outcomes

  1. Changes of the Cardiac Index (CI) during the course of hemodialysis therapy

    Time frame: from baseline to 6 months

  2. Changes of the Oxygen delivery ( Adequacy of hemoglobin level to Epoetin) during the course of hemodialysis therapy

    Time frame: from baseline to 6 months

Sponsors and collaborators

Lead sponsor

Sun Yat-sen University

Other

Registry information

Official study title

Study of Access Flow ,Access Recirculation of Arteriovenous Fistula and the Relationship With Cardiac Function

Important dates

Study start
2009
Primary completion
2012
Study completion
2012
First posted
Apr 22, 2016
Registry last updated
Apr 26, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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