The Relationship Between Serum and Urinary Angiotensinogen Levels and Long-Term Renal Prognosis in Acute Renal Injury

This study aims to retrospectively examine long-term (at the end of the 3rd year) renal function in the thesis study titled "Investigation of serum and urine angiotensinogen levels as a prognostic indicator of renal function in acute kidney injury," which received approval from the Tokat Gaziosmanpaşa University Faculty of Medicine ethics committee in 2019 (approval number 19-KAEK-052). Thus, the relationship between serum and urine angiotensinogen levels and long-term renal function will be investigated, and the importance of this biomarker in the development of chronic kidney disease (CKD) in patients with acute kidney injury (AKI) will be examined.

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Key information

Conditions

In Acute Kidney Injury

Sex eligibility

All sexes

Study type

Observational

Primary location

Mehmet Akif İnan Hospital

Karaköprü, Şanlıurfa, 6300, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

PATIENTS DEVELOPING KIDNEY FAILURE

Exclusion criteria

MALIGNANT PATIENTS

Treatment and study plan

Primary outcomes

The relationship between serum and urinary angiotensinogen levels and renal function at the end of the 3rd year in patients who developed acute kidney injury.

Time frame: Patients admitted to intensive care and who developed renal failure between January 2018 and January 2020.

serum and urinary angiotensinogen levels

Secondary outcomes

The relationship between serum and urinary angiotensinogen levels and renal function at the end of the 3rd year in patients who developed acute kidney injury.

Time frame: Patients who were alive after 2020 and whose kidney function tests were measured at the end of the 3rd year.

serum and urinary angiotensinogen levels

Sponsors and collaborators

Lead sponsor

Sanliurfa Mehmet Akif Inan Education and Research Hospital

Other

Registry information

Acronym: Renal Injury

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Apr 6, 2026
Registry last updated: Apr 6, 2026

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.