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OpenTrials
Completed

NCT Number: NCT06384703

The Relationship Between Microbiota and Coronary Ectasia

Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.

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Key information

Conditions

Coronary Ectasia Microbial Disease

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Necmettin Erbakan University

Konya, 42050, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over 18 years old
  • not having occlusive coronary artery disease
  • having coronary ectasia

Exclusion criteria

  • patients with chronic kidney disease,
  • revascularized coronary artery disease,
  • previously documented critical coronary stenosis,
  • acute or chronic inflammatory disease,
  • rheumatologic disease,
  • known active malignant disease,
  • heart failure,
  • moderate-to-severe valvular pathology
  • patients who were on any steroid or immunosuppressive therapy

Treatment and study plan

Taking blood for kit study

Diagnostic Test

Taking blood for kit study (Elisa kit)

Primary outcomes

  1. death

    Time frame: 1 month

    Death from any cause within the last month

Sponsors and collaborators

Lead sponsor

Konya Beyhekim Training and Research Hospital

Other Gov

Collaborators

  • Necmettin Erbakan University

Registry information

Official study title

The Evaluation of the Relationship Between Coronary Ectasia And Trimethylamine N Oxide

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Apr 25, 2024
Registry last updated
Apr 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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