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Completed

NCT Number: NCT05677165

The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study

By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot), Driving Pressure Saturation Index (OSIDP), Dynamic Power Saturation Index (OSIMPdyn) ve Power Saturation Index (OSIMPtot).

New oxygenation and saturation indices are able to predict ICU mortality better than the conventional indexes and rates.

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Key information

Conditions

Acute Respiratory Distress Syndrome Infections Lung Diseases Pneumonia Respiration Disorders Respiratory Distress Syndrome Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bakirköy Dr sadi konuk Education hospital

Istanbul, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with a diagnosis of Covid-19 related Acute Respiratory Syndrome (C-ARDS) which hospitalized in Bakirköy Dr. Sadi Konuk Training and Research Hospital intensive care unit

Exclusion criteria

  • Patients who did not receive invasive mechanical ventilation support.
  • Patients who stayed in the intensive care unit for less than 24 hours.
  • Patients with missing data
  • Patients who received mechanical ventilation support for less than 24 hours
  • Patients with Chronic Obstructive Pulmonary Disease (COPD).
  • Patients with congestive heart failure
  • Patients who underwent tube thoracostomy due to tension pneumothorax
  • Patients who received Extracorporeal Membrane Oxygenation (ECMO) support

Treatment and study plan

Primary outcomes

  1. In hospital mortality

    Time frame: 28 days

    we estimate hospital mortality mortality by calculating new oxygenation index

Secondary outcomes

  1. Mechanical ventilatory free days

    Time frame: 30 days

    we estimate hospital mortality mortality by calculating new saturation index

Sponsors and collaborators

Lead sponsor

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Other Gov

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jan 10, 2023
Registry last updated
Jan 10, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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