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Completed

NCT Number: NCT05294224

The Relationship Between Disease Severity and Various Lower Extremity Parameters in Individuals With Knee Osteoarthritis

This study perform to investigate the relationship between quadriceps femoris (QF) strength, QF thickness, femoral cartilage thickness, knee function, balance, kinesiophobia and gait of the patients with knee osteoarthritis.

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Key information

Conditions

Knee Osteoarthritis Anxiety Disorders Arthritis Joint Diseases Kinesiophobia Knee Injuries Leg Injuries Mental Disorders Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Phobic Disorders Rheumatic Diseases Wounds and Injuries

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Mugla Sıtkı Koçman University

Muğla, 48000, Turkey (Türkiye)

About this study

Osteoarthritis (OA) is one of the most common chronic degenerative diseases in the world, which progresses slowly, can cause pain, stiffness and dysfunction, and reduces the quality of life.

OA is particularly common in weight-bearing joints such as the knee and the functional status of patients with OA is adversely affected various factors such as immobility due to pain, decrease in muscle strength and joint range of motion, etc.

In relation to this, walking difficulty and decrease in walking speed, balance problems and an increase in the risk of falling are a picture that can be encountered in the later stages of the disease.

The aim of this study is to investigate the relationship between QF strength, QF thickness, femoral cartilage thickness, knee function, balance, kinesiophobia and gait of the patients with knee OA.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteer patients who applied to the Physical therapy and Rehabilitation department with knee pain

Exclusion criteria

  • Individuals who have received intra-articular therapy for gonarthrosis in the last 6 months, who have undergone arthroscopic surgery, and who have additional pathologies in their lower extremities
  • Individuals with physical, mental and/or psychological disorders that may affect participation in the study

Treatment and study plan

Primary outcomes

  1. QF muscle thickness

    Time frame: Day 1

    QF muscle thickness

  2. QF muscle strength

    Time frame: Day 1

    QF muscle strength

  3. Femoral cartilage thickness

    Time frame: Day 1

    Femoral cartilage thickness

  4. Knee function

    Time frame: Day 1

    Knee function assessment with The Knee injury and Osteoarthritis Outcome Score (KOOS). It is a 42-item questionnaire, including 5 subscales: symptoms, pain, ADLs, sports/recreation, and quality of life. The maximum score a patient can achieve is 100, indicating no knee problems. The minimum score is zero, indicating severe knee problems.

  5. Kellgreen-Lawrence Radiological Stages

    Time frame: Day 1

    Kellgreen-Lawrence Radiological Stages:

    Grade 1 (doubtful): doubtful joint space narrowing and possible osteophytic lipping. grade 2 (minimal): definite osteophytes and possible joint space narrowing. grade 3 (moderate): moderate multiple osteophytes, definite narrowing of joint space and some sclerosis and possible deformity of bone ends.

  6. Kinesiophobia

    Time frame: Day 1

    Tampa Kinesiophobia Scale: The total score of the scale range from 17- 68, where 17 means no kinesiophobia, 68 means severe kinesiophobia, and score ± 37 indicates there is kinesiophobia.

  7. Balance and gait

    Time frame: Day 1

    Tinetti Score: It uses a 3-point ordinal scale of 0, 1 and 2. Gait is scored over 12 and balance is scored over 16 totalling 28. The lower the score on the Tinetti test, the higher the risk of falling.

  8. Low Extremity Functionality and Fall Risk

    Time frame: Day 1

    30 sec sit to stand test

Sponsors and collaborators

Lead sponsor

Dilara Özen Oruk

Other

Collaborators

  • Muğla Sıtkı Koçman University

Registry information

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
Mar 24, 2022
Registry last updated
Mar 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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