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Completed

NCT Number: NCT06246201

The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients

The study aimed to examine the relationship between cognitive status, exercise capacity, and fatigue perception in coronary artery disease patients.

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Key information

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hacettepe University

Ankara, Turkey (Türkiye)

About this study

Exercise training for patients with coronary artery disease is an essential element of multicomponent cardiac rehabilitation. For the successful implementation of exercise-based cardiac rehabilitation programs, adequate cognitive function (e.g. executive function, selective attention, memory) is an important prerequisite. In patients with atherosclerotic coronary artery disease, the presence of coronary microvascular dysfunction as determined by low coronary flow reserve is associated with abnormal cerebral flow hemodynamics and mild but significant impairment in cognitive function. In the literature, there is no study examining the relationship between cognitive level and fatigue perception.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteering to participate in the research
  • Being diagnosed with coronary artery disease
  • To cooperate with the tests to be performed
  • Signing a consent form

Exclusion criteria

  • Presence of neurological disease that may affect cognitive status
  • Presence of clinically unstable cardiac disease
  • Left ventricular ejection fraction <30%
  • Being diagnosed with end-stage renal failure
  • Diagnosed with active myocarditis or pericarditis
  • Being diagnosed with rhythm disorder
  • Having amputation, peripheral arterial disease, musculoskeletal and/or neurological diseases that will prevent participation in functional capacity tests
  • Not volunteering to participate in the study

Treatment and study plan

Primary outcomes

  1. Cognitive State Assessment

    Time frame: August 2023-August 2024

    Montreal Cognitive Assessment Scale (MoCA) will be used to assess cognitive status.

  2. Assessment of Exercise Capacity

    Time frame: August 2023-August 2024

    Exercise capacity will be evaluated with modified shuttle walking test.

  3. Assessment of Perceived Fatigue Severity After Exercise Test

    Time frame: August 2023-August 2024

    It will be evaluated on the Modified Borg Scale from 0 to 10. 0 means no fatigue. 10 means extremely tired.

Secondary outcomes

  1. Physical Activity Assessment

    Time frame: August 2023-August 2024

    Physical activity level will be measured with the International Physical Activity Questionnaire (IPAQ). 600 METs (Metabolic Equivalent of Task) min/week means inactive.

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

An Investigation of The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Feb 7, 2024
Registry last updated
Feb 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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