The Prognostic Role of Tricuspid Annular Plane Systolic Excursion in Critically Ill Patients With Septic Shock

The aim of this study is to evaluate the possible prognostic performance of RV dysfunction, as assessed by TAPSE, in non-cardiac patients with septic shock.

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Key information

Conditions

Septic Shock Infections Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms Sepsis Shock Shock, Septic Systemic Inflammatory Response Syndrome

Age range

18 year–64 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine, Alexandria University Hospitals

Alexandria, Egypt

About this study

The objective is to investigate the prognostic performance of right ventricular dysfunction, as assessed by tricuspid annular plane systolic excursion (TAPSE), in non-cardiac patients with septic shock.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients (18 - 64 years old) with septic shock after admission according to 2016 consensus definition (Sepsis-3).

Exclusion criteria

Pregnant females
Trauma
Documented coronary heart disease
History of myocardial infarction
Myocarditis
Thrombo-embolic pulmonary disease
Valvular heart disease
Corpulmonale
Arrhythmia
Known left ventricular ejection fraction < 40%
Poor echocardiographic window

Treatment and study plan

tricuspid annular plane systolic excursion (TAPSE)

Radiation

Echocardiography

Primary outcomes

28-day mortality

Time frame: Day 28

Mortality rate after at day 28.

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Important dates

Study start: 2023
Primary completion: 2023
Study completion: 2023
First posted: Aug 23, 2023
Registry last updated: Aug 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed