Study product A (Wonderlab wonder4shape)
Dietary SupplementParticipants in this arm need to consume one bottle (2g) of this product once a day for 10 weeks
NCT Number: NCT06030999
The goal of this interventional study is to test whether consumption of Wonderlab probiotics with prebiotics could improve obesity and overweight in Chinese people who are aged 25-45 and overweight. The main question it aims to answer is:
- whether the weight of participants can be lost after 10 weeks' intervention
150 participants will be randomized into 3 study groups (50 each group) in the two study sites, who will consume assigned product according to instructions for 10 weeks. Three site visits will be made for each participant and all relevant clinical data will be captured and recorded into CTMS(Clinical Trial Management System) for statistical analysis.
Researchers will compare the three groups to conclude whether the Wonderlab study product can improve obesity and overweight over placebo product.
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Notify Me25 year–45 year
All sexes
Interventional
Not applicable
SPRIM Central Lab, Shanghai, Shanghai Municipality, China
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants in this arm need to consume one bottle (2g) of this product once a day for 10 weeks
Participants in this arm need to consume one bottle (2g) of this product once a day for 10 weeks
Participants in this arm need to consume one bottle (2g) of this product once a day for 10 weeks
Time frame: baseline day 0, day 70
Change of Weight in Kg by Inbody S10 from baseline to 10 weeks
Time frame: baseline day 0, day 35, day 70
Blood lipids - Total Cholesterol level of blood test in mmol/L and range of 0.56-17mmol/L for each visit interval
Time frame: baseline day 0, day 35, day 70
Blood sugar level of blood test in mmol/L and range of 3.9-6.1mmol/L
Time frame: baseline day 0, day 35, day 70
Blood hormone - Leptin level of blood test in ng/mL and range 0.5-15.2ng/mL
Time frame: baseline day 0, day 35, day 70
Blood hormone - Adiponectin level of blood test in ug/mL and range of 2-37ug/mL
Time frame: baseline day 0, day 35, day 70
Blood inflammation (Zonulin, ApoB-48, hsCRP, LPS, sCD14, IL-6, MCP-1, Angptl4)
Shenzhen Precision Health Food Technology Co. Ltd.,
Other Gov
Three Arms, Randomized, Double-blind Controlled Trial Of Prevention And Treatment On Obesity And Weight Management By Oral Supplementation Of Probiotics And Prebiotics
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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