The Preoperative Health & Body Study

Inclusion criteria

• Newly diagnosed, histologically confirmed stage I-III breast cancer
• Planning to undergo definitive surgical management with lumpectomy or mastectomy with in the next 8 weeks.
• Willing and able to participate in the intervention for at least 3 weeks prior to surgery.
• ECOG performance status of 0 or 1
• Approval by oncologist or surgeon
• Willingness to be randomized.
• English speaking and able to read English

Exclusion criteria

• Concurrent other malignancy or history of other malignancy treated within the past 3 years (other than non-melanoma skin cancer or in situ cervical cancer)
• Presence of metastatic disease
• Scheduled to receive any form of neoadjuvant cancer therapy
• Locally advanced breast cancer not amenable to primary surgery
• History of prior ipsilateral breast cancer
• Taking tamoxifen, raloxifene or an aromatase inhibitor at the time of breast cancer diagnosis
• Absolute contraindications to maximal exercise testing as recommended by the American Thoracic Society
• Any condition which in the investigator's opinion makes the subject unsuitable for study participation
• Participating in another clinical study with competing study outcomes
• Pregnant (i.e., positive beta-HCG) or breast feeding
• Unable to comply with protocol and/or not available for follow-up assessments
• Participation in more than 90 minutes a week of moderate-intensity recreational activity (not including activities such as gardening, bowling, golfing with a cart) as assessed by the Leisure Score Index of Godin Leisure- Time Exercise Questionnaire (LSI) (Appendix I) or recent participation (past 6 months) in two or more strength training sessions per week.
• Diabetes mellitus requiring insulin or oral agents; patients with diet-controlled diabetes will be allowed to participate