Skip to main content
OpenTrials
Completed

NCT Number: NCT02561468

The Preemptive Analgesic Efficacy of Nefopam

Nefopam is administered as a preemptive analgesic drug to the patient undergoing breast cancer surgery. It will be evaluated whether postoperative acute and chronic pain can be reduced.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Breast Neoplasm Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Age range

20 year–80 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, 443-607, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with breast cancer
  • Lumpectomy with axillary lymph node dissection or Lumpectomy with sentinel lymph node biopsy
  • American Society of Anesthesiologists physical status I or II

Exclusion criteria

  • Refusal
  • Seizure
  • Cardiac disease
  • Monoamine oxidase inhibitor user
  • Urologic disease
  • Glucoma
  • Preoperative analgesic drug medication
  • Pregnancy
  • Recurred breast cancer patient

Treatment and study plan

Nefopam

Drug

Saline

Drug

Primary outcomes

  1. The change of pain numerical rating score from postoperative 30 min until postoperative 3 month

    Time frame: Postoperative 30 min, postoperative 1 day, postoperative 1 week, postoperative 3 month

Secondary outcomes

  1. The dose of ketorolac administered to the patient.

    Time frame: postoperative 1 day

Sponsors and collaborators

Lead sponsor

Seoul National University Bundang Hospital

Other

Registry information

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Sep 28, 2015
Registry last updated
Apr 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.