the Prediction Value of Combined Electroencephalographic and Electromyographic Response in Disorders of Consciousness

Inclusion criteria

• Age ≥18 years.
• Brain damage lasts 28 to 90 days.
• It meets the diagnostic criteria of unresponsive arousal syndrome/vegetative state (UWS/VS) or microconscious state (MCS).

Diagnostic criteria for UWS/VS: loss of cognitive function and inability to execute commands; There is a sleep-wake cycle; Inability to understand or express language; The ability to open eyes automatically or in response to stimulation; Can be purposeless eye following movement; The functions of hypothalamus and brainstem were basically preserved.

MCS diagnostic criteria: simple instructions can be executed; Yes/no (whether correct or not) can be expressed by gesture or speech; Have an understandable language; Purposeful behavior (including activity or emotional response) with more than one can diagnose MCS.

• All subjects' legal guardians sign informed consent forms.

Exclusion criteria

• Spinal cord T1 and above plane injury, peripheral nerve injury and so on affect nerve conduction;
• The impact of injury on palms and soles of feet;
• History of developmental, psychiatric, or neurological disorders prior to brain injury.
• Deep sedation within 72 hours, including the use of general anesthesia.
• Increased intracranial pressure, liver/kidney failure, and hemodynamic instability within 72 hours.
• Severe co-existing systemic diseases with limited life expectancy.