The Pancreatic Enzymes After Gastrectomy Trial

Inclusion criteria

• Gastrectomy (total and partial); at least > 50 % of the stomach must be resected
• Age 18 or older
• Written informed consent

Exclusion criteria

• Indication for pancreas enzyme therapy
• Gastrectomy with palliative intention
• UICC (Union for International Cancer Control) Stage IV gastric malignancy
• Malnutrition of other aetiology
• Life expectancy < 12 months
• Known lactose intolerance
• Known hereditary galactose intolerance
• Patients on alpha-glucosidase inhibitors (AGIs)
• Acute pancreatitis
• Acute episode of chronic pancreatitis
• Known hypersensitivity to moulds (mould allergy) or any other ingredient of NORTASE®
• Participation in competing interventional trials may be allowed under circumstances
• Patients under legal supervision or guardianship
• Patients who are dependent on the investigator or the medical staff of the trial team or the coordinating investigator or the sponsor
• Fertile women (within two years of their last menstruation) without appropriate contraceptive measures (implanon, injections, oral contraceptives, intrauterine devices, partner with vasectomy) while participating in the trial
• Pregnant or nursing women
• Suspected lack of compliance
• Patients who were already enrolled in the trial