The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

The long-term goal of our PIC is to develop effective strategies that can be applied clinically at the point-of-care to prevent, intercept, or detect PDAC at an early stage, thereby reducing PDAC burden and saving lives.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Pancreatic Ductal Adenocarcinoma Ataxia Ataxia Telangiectasia BRCA Mutation Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebellar Ataxia Cerebellar Diseases Chronic Disease Chronic Pancreatitis Colonic Diseases Colorectal Neoplasms Colorectal Neoplasms, Hereditary Nonpolyposis Congenital, Hereditary, and Neonatal Diseases and Abnormalities Cysts DNA Repair-Deficiency Disorders Digestive System Diseases Digestive System Neoplasms Disease Attributes Dyskinesias Dysplastic Nevus Syndrome FAP Familial Atypical Multiple Mole-Melanoma Fatty Pancreas Gastrointestinal Diseases Gastrointestinal Neoplasms Genetic Diseases, Inborn Genetic Pancreatic Cancer Genetic Pancreatitis Hyperpigmentation Immune System Diseases Immunologic Deficiency Syndromes Intestinal Diseases Intestinal Neoplasms Intestinal Polyposis Lentigo Lynch Syndrome Melanosis Metabolic Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplastic Syndromes, Hereditary Nervous System Diseases Neurocutaneous Syndromes Neurologic Manifestations Nevi and Melanomas Nevus Nutritional and Metabolic Diseases PALB2 Gene Mutation Pancreatic Cyst Pancreatic Diseases Pancreatitis Pancreatitis, Chronic Pathologic Processes Pathological Conditions, Signs and Symptoms Peutz-Jeghers Syndrome Pigmentation Disorders Primary Immunodeficiency Diseases Skin Diseases Skin and Connective Tissue Diseases Spinocerebellar Ataxias Telangiectasis Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Moffitt Cancer Center

Tampa, Florida, 33617, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years of age or older
Moffitt Cancer Center patients presenting with a pancreatic cyst, and/or inherited syndrome that predisposes them to pancreatic ductal adenocarcinoma (PDAC)
Moffitt Cancer Center patients undergoing evaluation for localized/early stage PDAC.
Moffitt Cancer Center patients with a combination of PDAC risk factors such as a history of chronic or new-onset diabetes, pancreatitis, obesity, tobacco exposure, toxin exposure and/or heavy alcohol consumption.

Treatment and study plan

Data Collection

Other

Investigators will compile data typically collected clinically. This data will include demographics, cancer screening procedures, cancer diagnosis and staging, chemotherapy, immunotherapy, radiation therapy, surgery, comorbidities, medication use, lifestyle and other cancer risk factors, quality of life, vital status, and molecular data generated from specimens collected clinically.

Primary outcomes

Database creation

Time frame: 24 months

A centralized, real-time, queryable and secure database will be developed that will integrate data on Moffitt patients diagnosed with pancreatic ductal adenocarcinoma (PDAC), pancreatic cystic lesions (benign, pre-cancerous and malignant), or an inherited PDAC susceptibility.

Sponsors and collaborators

Lead sponsor

H. Lee Moffitt Cancer Center and Research Institute

Other

Registry information

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2026
First posted: Jan 20, 2023
Registry last updated: Apr 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting