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Completed

NCT Number: NCT06824428

The Pain Perception Threshold in Attention Deficit Disorder With Hyperactivity

The aim of this study was to evaluate whether the disease subtype affects the presence of chronic pain and pain perception threshold in pediatric patients followed up with the diagnosis of attention deficit and hyperactivity disorder, and to evaluate the factors that may be related to pain perception threshold in disease subtypes.

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Key information

Conditions

Pain Threshold Attention Deficit Disorder With Hyperactivity (ADHD) Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Mental Disorders Neurodevelopmental Disorders

Age range

6 year–17 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sultan 1. Murat State Hospital

Edirne, 22030, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with attention deficit and hyperactivity disorder according to DSM-5 diagnostic criteria
  • Being between the ages of 6-17
  • Being at a clinically normal mental level

Exclusion criteria

  • Having verbal and visual communication problems
  • Having a history of perinatal complications or physical head trauma
  • Having comorbid psychiatric disorders other than oppositional defiant disorder and conduct disorder
  • Known history of chronic physical and neurological disease (such as cerebral palsy, diabetes, epilepsy, autoimmune diseases, liver and kidney failure)
  • Presence of substance or alcohol use disorder
  • Having a genetic disorder diagnosis

Treatment and study plan

Pain perception threshold

Other

The patients' pressure pain threshold will be evaluated with a manual pressure algometer (Baseline Dolorimtre®).The patients' pain perception thresholds will be measured bilaterally in the midfrontal region, the midpoint of the trapezius muscle, the lateral epicondyle, the midpoint of the web between the 1st and 2nd fingers, the greater trochanter, and the medial crease of the knee.

Primary outcomes

  1. pressure pain threshold

    Time frame: Baseline

    The pressure pain threshold will be assessed with a manual pressure algometer (Baseline Dolorimtre®). The patients' pain perception thresholds will be measured bilaterally in the midfrontal region, the midpoint of the trapezius muscle, the lateral epicondyle, the midpoint of the web between the 1st and 2nd fingers, the greater trochanter, and the medial crease of the knee. During the measurement, the 1.52 cm2 flat circular probe of the algometer will be placed on the relevant area and the pressure will be increased by 1 kg/second. Patients will be asked to express their pain by saying 'stop' or raising their hands when they feel slight discomfort. The value for each reference area will be obtained by calculating the arithmetic mean of the paired measurements.

Secondary outcomes

  1. Presence of chronic pain

    Time frame: Baseline

    It will be questioned whether there has been continuous pain in any part of the body for at least 3 months.

  2. Pain score

    Time frame: Baseline

    The patients' pain score will be evaluated with the Numerical Rating Scale (NRS). A 10 cm long horizontal straight line will be used in the NRS evaluation. Before the evaluation, the patient will be informed that a value of 0 represents no pain and a value of 10 represents the most severe pain felt to date. Patients will be asked to answer by considering the average of their pain over the last 3 days.

  3. Duration of chronic pain

    Time frame: Baseline

    The duration of pain that has continued for at least 3 months in any part of the body will be questioned.

  4. Sociodemographic data of patient

    Time frame: Baseline

    gender, age, height, weight, age of onset of complaints, duration of medication use, number of siblings, primary caregiver

  5. Sociodemographic data of patient's parents

    Time frame: Baseline

    Age, occupation, education level and psychiatric disease history of mother and father

Sponsors and collaborators

Lead sponsor

Sultan 1. Murat State Hospital

Other Gov

Registry information

Official study title

Can the Disease Subtype Affect the Pain Perception Threshold in Children Diagnosed With Attention Deficit Disorder With Hyperactivity?

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 13, 2025
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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