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OpenTrials
Active, Not Recruiting

NCT Number: NCT05988983

The Over The Counter Pill National Study

This is a prospective cohort study of individuals purchasing the oral contraceptive pill over the counter (OTC) in pharmacies in 32 US states. The comparison group is people receiving a prescription (Rx) for oral contraception. Both groups will be followed for one year to examine contraceptive continuation rates. This study will also identify who is using the pill OTC and why and evaluate differences in pregnancy intention and measures of contraceptive agency between the two groups.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Contraception Behavior Contraception Behavior Contraceptive Usage Health Behavior Health Care Utilization Patient Acceptance of Health Care Reproductive Behavior Treatment Adherence and Compliance

Age range

12 year–51 year

Sex eligibility

Female

Study type

Observational

Primary location

Oregon Health & Science University

Portland, Oregon, 97239, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Capable of pregnancy
  • Purchasing oral contraception at a participating pharmacy

Exclusion criteria

  • Using the pill for non contraceptive indications

Treatment and study plan

Availability of OTC contraceptive pill

Other

Over the counter contraceptive pill

Primary outcomes

  1. 12 month contraceptive continuation rates

    Time frame: 12 months

    Difference in proportion of participants using contraception 12 months after starting between over the counter and prescription groups.

Sponsors and collaborators

Lead sponsor

Oregon Health and Science University

Other

Collaborators

  • Arnold Ventures

Registry information

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Aug 14, 2023
Registry last updated
May 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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