The Noninvasive Ventilation to COVID-19 Patients

Noninvasive ventilation(NIV) is an important treatment to the respiratory failure patients.The severe Corona Virus Disease-19(COVID-19) patients are incline to respiratory failure.The NIV may reduce the intubtion rate.This research was taken to investigate the factor to the success of the noninvasive ventilation to the COVID-19 patients with respiratory failure.We wish to raise the success rate to COVID-19 patients with respiratory failure.More critically ill COVID-19 patients could avoid the intubtion.

Inclusion criteria

• Shortness of breath, RR>30 times per minute;
• At room air, SpO2 lower than 93%;
• The partial pressure of Arterial blood oxygen (PaO2)/the fraction of inspired oxygen (FiO2) ≤ 300mmHg;
• CT（computed tomography） chest imaging shows that lung damage develops significantly within 24 to 48 hours.

Exclusion criteria

• Severe cardiovascular disease,
• respiratory arrest,
• cardiovascular instability (hypotension, arrhythmias, myocardial infarction),
• change in mental status or patients who were uncooperative, high risk of aspiration, viscous or copious
• secretions,
• recent facial or gastroesophageal surgery,
• craniofacial trauma, 8)fixed nasopharyngeal abnormalities,

9）burns, 10) extreme obesity.