The No-Tie Technique Using the Harmonic Scalpel in Total Thyroidectomy With Central Neck Dissection: A Prospective Randomized Study

To investigate the safety and efficacy of the no-tie technique using the harmonic scalpel (HS) in terms of the operating time and complications in total thyroidectomy with central neck dissection (CND). Recently, the HS has been used as an alternative to conventional hand-tied ligation for hemostasis in thyroid surgery, which is a time-consuming procedure. Very limited data have been published on evidence of its safety in total thyroidectomy accompanied by CND without supplementary hand-tied ligation.

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Key information

Conditions

Hemorrhage Calcium Metabolism Disorders Cranial Nerve Diseases Hypocalcemia Laryngeal Diseases Metabolic Diseases Nervous System Diseases Neurologic Manifestations Nutritional and Metabolic Diseases Otorhinolaryngologic Diseases Paralysis Pathologic Processes Pathological Conditions, Signs and Symptoms Respiratory Tract Diseases Signs and Symptoms Vagus Nerve Diseases Vocal Cord Palsy Vocal Cord Paralysis Water-Electrolyte Imbalance

Sex eligibility

All sexes

Study type

Observational

Primary location

Dept. of otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine

Bucheon-si, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with total thyroidectomy plus central neck dissection
if primary tumor size was more than 1 cm in papillary thyroid cancer
there was any evidence of lymph node enlargement in paratracheal lymph node group preoperatively or intraoperatively
patients who underwent minimal resection of the surrounding soft tissues, including the sternothyroid or sternohyoid muscle, for extracapsular extension of thyroid cancer

Exclusion criteria

patients who required lateral compartment neck dissection or mediastinal dissection for preexisting lymph node metastasis
patients had clinical or laboratory indicators of coagulation disorders
patients with preexisiting vocal cord palsy, fixation of the tumor to the recurrent laryngeal nerve requiring trnasection of the nerve
patients with massive extracapsular extension to the surrounding soft tissues.

Sponsors and collaborators

Lead sponsor

Soonchunhyang University Hospital

Other

Registry information

Important dates

Study start: 2006
Study completion: 2007
First posted: Jul 25, 2007
Registry last updated: Jul 26, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed