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Completed

NCT Number: NCT04720781

The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

After vonoprazan (20mg/day) or esomeprazole (20mg/day) for 4weeks is prescribed for patients with erosive esophagitis diagnosed by esophagogastroduodenoscopy, the number of patients who will visit our outpatient clinic again due to some reasons without any appointments is compared with vonoprazan group and esomeprazole.

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Key information

Conditions

Gastroesophageal Reflux Deglutition Disorders Digestive System Diseases Esophageal Diseases Esophageal Motility Disorders Gastrointestinal Diseases

Age range

19 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Showa Inan General hospital

Komagane, Nagano, 399-4191, Japan

About this study

  • Patients who have erosive esophagitis diagnosed by esophagogastroduodenoscopy is enrolled.
  • Vonoprazan (20mg/day) or esomeprazole (20mg/day) is prescribed for 4weeks the patients randomly without next appointments.
  • Some patients may visit our outpatient clinic again due to some reasons without any appointments.
  • The number of the patients who revisit our outpatient clinic again is compared with vonoprazan group and esomeprazole.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • outpatients belonging to American Society of Anesthesiologists class I or II
  • patients have erosive esophagitis diagnosed by esophagogastroduodenoscopy shortly before the prescription

Exclusion criteria

  • other acid blockers are taken

Treatment and study plan

Vonoprazan

Drug

Vonoprazan (20mg/day) is prescribed for 4 weeks.

Other names: Esomeprazole

Esomeprazole

Drug

esomeprazole (20mg/day)

Primary outcomes

  1. The number of patients who revisit our outpatient clinic after the prescription without any appointments

    Time frame: 3 months

    The need to revisit our outpatient clinic again without any appointments may show the patients' satisfaction or dissatisfaction after the prescription of vonoprazan or esomeprazole. The difference in the number between the two groups may show the difference in the effectiveness between the two medicines.

Secondary outcomes

  1. Change of the main symptom with patients after/before medication when the patients revisit again

    Time frame: 3 months

    The ratio of the degree of the main symptom after/before taking the medicine Good 0%- Bad 100%

Other outcomes

  1. Questionnaire on satisfaction with taking the medicine at revisiting

    Time frame: 3months

    The patient's satisfaction is assessed using visual analogue scale (Exellent 100% to very bad 0%).

Sponsors and collaborators

Lead sponsor

Showa Inan General Hospital

Other

Registry information

Official study title

The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole for 4weeks for Erosive Esophagitis Without Any Appointments

Important dates

Study start
2021
Primary completion
2024
Study completion
2024
First posted
Jan 22, 2021
Registry last updated
May 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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