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Completed

NCT Number: NCT04250740

The Morning Coffee Study

The liking of a breakfast meal has been shown to influence food choice throughout the day. This study will investigate the effects that liking of different coffee beverages has on daily food intake.

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Key information

Age range

20 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University of Guelph

Guelph, Ontario, N1G 2W1, Canada

About this study

This is a postprandial acute meal crossover blinded study in which 30 fasted young healthy women will consume one of 3 butter-rich coffees, in random order, at each of three study sessions separated by at least 4 days. Participants will rate the coffee characteristics and complete paper visual analogue scale ratings of alertness, fatigue, nausea, satiety, and comfort for 180 minutes and consume a pasta lunch meal. A subset of 10 participants will be invited to attend 3 additional study visits where gastric emptying following consumption of each coffee will be assess using gastric ultrasound.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Generally healthy women
  • 20-35 yrs
  • BMI of 18.5-26.1 kg/m2 and waist circumference <88cm
  • Non-smoking
  • Non to moderate alcohol drinkers
  • Regular coffee consumers
  • Regularly consumes dairy products
  • Pre-menopausal with regular monthly periods
  • Stable medication use
  • Have not gained or lost significant weight during the past 3 months
  • Not pregnant or lactating
  • Enjoy and be willing to consume pasta with tomato sauce

Exclusion criteria

  • Any food sensitivity or intolerance
  • Any anaphylactic allergy or gastrointestinal disorder
  • History of any major disease or medical condition
  • Elite or training athletes
  • Three Factor Eating Questionnaire restraint score >16
  • Taking any natural health products or dietary supplements, other than a multivitamin, that interfere with fat or caffeine digestion

Treatment and study plan

Coffee with butter-1

Other

250 mL brewed black coffee with hazelnut flavouring and 50 g water

Coffee with butter-II

Other

250 mL brewed black coffee with hazelnut flavouring and 50 g unsalted butter-I

Coffee with butter-III

Other

250 mL brewed black coffee with hazelnut flavouring and 50 g unsalted butter-II

Primary outcomes

  1. Please indicate how much you liked or disliked the coffee

    Time frame: 30-180 minutes

    Hedonic scale ratings of beverage liking; 9 points from Dislike Extremely to Like Extremely

Secondary outcomes

  1. Please indicate on the line the creaminess of the coffee

    Time frame: 0 - 180 minutes

    Visual analogue scale ratings of product attributes; 0-100 mm from Not Creamy at All to Extremely Creamy

  2. Please indicate on the line how hungry you are

    Time frame: 30 - 180 minutes

    Visual analogue scale ratings of product attributes; 0-100 mm from Not Hungry at All to Extremely Hungry

  3. Lunch meal food intake

    Time frame: 180 minutes

    Weight of food consumed at ad libitum pasta meal

Other outcomes

  1. Gastric emptying

    Time frame: 0, 30, 60, 90, 120, 150, and 180 minutes

    Determined by gastric ultrasound assessment of gastric antrum cross sectional area

Sponsors and collaborators

Lead sponsor

University of Guelph

Other

Registry information

Important dates

Study start
2020
Primary completion
2024
Study completion
2024
First posted
Jan 31, 2020
Registry last updated
Mar 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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