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Completed

NCT Number: NCT04721340

The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis

The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Aydin University

Istanbul, Küçükçekmece, Turkey (Türkiye)

About this study

Upper limb can be affected even in early stage in people with Multiple Sclerosis (pwMS). Manual dexterity is important to maintain upper limb function and 9-Hole Peg Test (9HPT) is used as gold standard to assess dexterity in pwMS. There are no studies evaluating manual dexterity with the Minnesota Manual Dexterity Test (MMDT) in pwMS. This study aims to:

  • reporting the results of manual dexterity using the Minnesota Manual Dexterity Test and comparing the test results with healthy volunteers,
  • examining the relationship between MMDT and 9HPT, ABILHAND, grip strength, pinch strength, fatigue.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • (1) age 18-65;
  • (2) definitive diagnosis of MS according to McDonald criteria;
  • (3) ability to read and write in Turkish.

Exclusion criteria

  • (1) acute attacks of MS (within 3 months);
  • (2) cognitive impairment (Mini Mental test result 24 points and below);
  • (3) having spasticity (3 and above according to Modified Ashworth Scale)
  • (4) any chronic disease other than MS;
  • (5) being addicted to alcohol or drugs,

Treatment and study plan

Test Group

Other

Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.

Control Grup

Other

Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.

Primary outcomes

  1. Minnesota Manual Dexterity Test

    Time frame: baseline (on the predetermined assessment day)

    to assess manual dexterity, higher scores mean a worse outcome.

Secondary outcomes

  1. 9-Hole Peg Test

    Time frame: baseline (on the predetermined assessment day)

    to assess manual dexterity. higher scores mean a worse outcome.

  2. ABILHAND

    Time frame: baseline (on the predetermined assessment day)

    to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome.

  3. grip strength

    Time frame: baseline (on the predetermined assessment day)

    using hand dynamometer. higher scores mean a better outcome.

  4. pinch strength

    Time frame: baseline (on the predetermined assessment day)

    using pinchmeter. higher scores mean a better outcome.

  5. Fatigue Severity Scale

    Time frame: baseline (on the predetermined assessment day)

    to assess fatigue. score range 0-7 point, higher scores mean a worse outcome.

Sponsors and collaborators

Lead sponsor

Istanbul Aydın University

Other

Registry information

Official study title

Upper Limb Assessment in Multiple Sclerosis: The Minnesota Manual Dexterity Test As A Measure Of Hand Function

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jan 22, 2021
Registry last updated
Jun 15, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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