Completed

NCT Number: NCT01956617

The Mininimum Effective Anaesthetic Volume of Local Anaesthetic in Ultrasound-guided "Shamrock" Lumbar Plexus Block

The "Shamrock method" is a new ultrasound-guided lumbar plexus block. The aim of the study is to determine the minimum effective volume of ropivacaine 0.5% required to produce an effective lumbar plexus block with this method. Using the Dixon and Massey up-and-down method study design, 30 patients scheduled for elective total hip and knee arthroplasty will be included in the study.

Completed

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Key information

Conditions

Mininimum Effective Anaesthetic Volume of Local Anaesthetic

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anaesthesia and Intensive Care Medicine, Oslo University Hospital, Oslo, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

orthopaedic patients scheduled for elective hip and knee arthoroplasty
ASA 1 - 2 or stable ASA 3
age between 18 and 70 years
good ability to communicate and to cooperate

Exclusion criteria

ASA > 3 or unstable ASA 3
BMI > 32
chronicle pain
nephrological diseases or nephropathy
known contraindications against the use of local anaesthetics
pregnancy

Treatment and study plan

Lumbar Plexus Block

Other

Primary outcomes

minimum effective volume

Time frame: from day 1 up to 20 weeks

The primary outcome measure (MEV) is based on 30 measurements in 30 patients (secondary outcome measure: block success). MEV is determined by Dixon and Massey up-and-down method when all patients have been tested in the study

Secondary outcomes

block success

Time frame: Day 1

45 minutes after lumbar plexus blockade was performed

Sponsors and collaborators

Lead sponsor

Oslo University Hospital