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Completed

NCT Number: NCT04654572

The Mechanical Properties of Burned Muscles

The investigate of mechanical properties of muscles in burned patients.

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Key information

Conditions

Burns Atrophy Muscle Loss Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms Stiffness Viscoelastic Properties Wounds and Injuries

Age range

18 year–64 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hasan kalyoncu üniversity

Gaziantep, 27144, Turkey (Türkiye)

About this study

The hypermetabolic response to severe burn is characterized by muscle protein catabolism. Current opinion states that the hypermetabolic state resolves soon after complete wound closure. Clinically, we have witnessed that burned patient appear to be hypermetabolic and catabolic long after full healing of their wounds. Our goal in this study was to determine muscle mechanical properties (tone, stiffness and elasticity) after burn.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • burned patient
  • major burn over %20 TBSA

Exclusion criteria

  • Amputation
  • Dead
  • Systemic disease and abuse

Treatment and study plan

Myotonometric measurement

Diagnostic Test

Myotonometric assessment can predict the muscle stiffness, tone and elasticity

Primary outcomes

  1. Stiffness

    Time frame: 6 week

    Myotonometric measurement was used to determine for muscle stiffness. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

  2. Elasticity

    Time frame: 6 week

    Myotonometric measurement was used to determine for muscle elasticity. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

  3. Tone

    Time frame: 6 week

    Myotonometric measurement was used to determine for muscle tone. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

Sponsors and collaborators

Lead sponsor

Hasan Kalyoncu University

Other

Registry information

Official study title

The Investigation of Muscle Mechanical Properties in Burned Patients.

Important dates

Study start
2018
Primary completion
2019
Study completion
2020
First posted
Dec 4, 2020
Registry last updated
Dec 16, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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