Skip to main content
OpenTrials
Recruiting

NCT Number: NCT04016649

The Mechanical Characterisation of Human Saphenous and Popliteal Vein

Non-interventional study aiming to ascertain the mechanical properties of human saphenous and popliteal vein tissue.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Peripheral Vascular Diseases Cardiovascular Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Limerick

Limerick, Ireland

Location status: Recruiting

Location contact

Fiona Leahy, CNM Research

CONTACT

[email protected]

061588394

About this study

The aim of this study is to mechanically characterise saphenous and popliteal vein segments that have been deemed waste following varicose vein procedures, lower limb amputation and lower limb bypass surgery.

By characterising the stress-stretch relationship of the vein vessel wall, treatment techniques can be better understood. Mechanical device design can be bteer informed and the the suitability of vein as a conduit for bypass and AVF procedures can be assessed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or Female patients aged 18 years or older
  • Patients undergoing varicose vein procedures or;
  • Patients undergoing lower limb amputation or;
  • Patients undergoing lower limb bypass surgery

Exclusion criteria

  • Patients unable to give informed consent
  • Seriously ill/unconscious patients

Treatment and study plan

Primary outcomes

  1. The identification of vein tissue mechanical distension and stretching properties.

    Time frame: 2 years

    Vein tissue will undergo inflation-extension testing and unilaxial testing. The vein tissue will be cross-sectioned and rings of venous tissue will be mechanically characterised according to the properties exhibited.

Study contacts

Contact information is provided by the study sponsor or research team.

Fiona Leahy, CNM Research

CONTACT

[email protected]

061588394

Sponsors and collaborators

Lead sponsor

University Hospital of Limerick

Other

Collaborators

  • University of Limerick

Registry information

Important dates

Study start
2019
Primary completion
2027
Study completion
2027
First posted
Jul 11, 2019
Registry last updated
Apr 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.