Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07467928

The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion

The goal of this prospective study is to to evaluate the prevalence of metachronous advanced colonic lesions in subsequent surveillance colonoscopies in patients who had previously undergone AI-assisted colonoscopy to conventional colonoscopy examinations.

The main question it aims to answer is whether employing AI-assisted colonoscopy can decrease the likelihood of metachronous advanced colonic lesions during subsequent surveillance colonoscopies.

Researchers will compare patient who undergo conventional colonoscopy in previous colonoscopy to see if AI-assisted colonoscopy can decrease the likelihood of metachronous advanced colonic lesions during subsequent surveillance colonoscopies. Participants will undergo surveillance colonoscopy to assess the presence of metachronous advanced colonic lesion

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Colonic Polyps Advanced Metachonous Colonic Lesion Artifical Intelligence Intestinal Polyps Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Polyps

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Queen Mary Hospital

Hong Kong

Location status: Recruiting

Location contact

Thomas KL Clinical Associate Professor, MD

CONTACT

[email protected]

852+97360997

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eligible participants are those who were previously enrolled and completed our randomized controlled trial comparing AI-assisted and conventional colonoscopy

Exclusion criteria

  • In addition to the baseline exclusion criteria of the index trial, patients who were found to have inflammatory bowel disease, colorectal cancer and underwent bowel resection would be excluded. Similar to index trial, patients who have developed severe comorbid illnesses that make surveillance colonoscopy and polypectomy unsafe, or become unable to provide informed consent for trial participation would also be excluded

Index trial: Lui TK, Lam CP, To EW, Ko MK, Tsui VWM, Liu KS, et al. Endocuff With or Without Artificial Intelligence-Assisted Colonoscopy in Detection of Colorectal Adenoma: A Randomized Colonoscopy Trial. Am J Gastroenterol. 2024;119(7):1318-25

Treatment and study plan

Suveillance colonoscopy

Procedure

Surveillance colonoscopy

Primary outcomes

  1. the cumulative risk of metachronous advanced colonic lesions

    Time frame: Three years

    the cumulative risk of metachronous advanced colonic lesions

Secondary outcomes

  1. cumulative risk of non-advanced metachronous adenoma and serrated lesions

    Time frame: three years

    cumulative risk of non-advanced metachronous adenoma and serrated lesions

  2. mean number of metachronous advanced colonic lesions

    Time frame: three years

    mean number of metachronous advanced colonic lesions

  3. mean number of metachronous adenomas, advanced adenomas, serrated lesions, and advanced serrated lesions

    Time frame: three years

    mean number of metachronous advanced colonic lesions, adenomas, advanced adenomas, serrated lesions, and advanced serrated lesions

Study contacts

Contact information is provided by the study sponsor or research team.

Thomas KL Clinical Assoicate Professor, MD

CONTACT

[email protected]

852 + 97360997

Sponsors and collaborators

Lead sponsor

The University of Hong Kong

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2028
First posted
Mar 12, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.