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OpenTrials
Completed

NCT Number: NCT06169345

The Long-term Course of Moderate Tricuspid Regurgitation

To evaluate the long-term clinical outcome of a cohort of patients suffering from moderate tricuspid regurgitation (TR), regardless of its etiology.

Completed

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Key information

Conditions

Tricuspid Regurgitation Cardiovascular Diseases Echocardiography Heart Diseases Heart Failure Heart Valve Diseases Tricuspid Valve Insufficiency

Age range

18 year–95 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Irccs San Raffaele

Milan, 20900, Italy

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with an echocardiographic diagnosis of moderate TR
  • Patients with echocardiographic and clinical follow-up information available at least 6-months after moderateTR diagnosis.

Exclusion criteria

  • Absence of an appropriate clinical and echocardiographic follow-up
  • A history of previous TV intervention (either surgical or percutaneous)
  • The presence of concomitant TV stenosis
  • Congenital heart disease
  • Left ventricular assist devices

Treatment and study plan

Echocardiographic evaluation

Other

Echocardiographic follow-up

Primary outcomes

  1. All-cause death

    Time frame: through study completion, an average of 2 years

    Time from diagnosis to all-cause death

Secondary outcomes

  1. Cardiovascular (CV) mortality

    Time frame: through study completion, an average of 2 years

    The occurrence of cardiovascular (CV) mortality (defined as death due to advanced heart failure, coronary ischemic heart disease, sudden cardiac death or due to stroke

Sponsors and collaborators

Lead sponsor

IRCCS San Raffaele

Other

Registry information

Official study title

The Long-term Clinical Course of Moderate Tricuspid Regurgitation

Acronym: LOCOMOTRI

Important dates

Study start
2021
Primary completion
2022
Study completion
2023
First posted
Dec 13, 2023
Registry last updated
Dec 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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