The Johns Hopkins Heartburn Center Registry

A multi-center, multi-year registry of patients with gastroesophageal reflux disease (GERD) undergoing diagnostic evaluation and/or treatment of GERD and associated diseases and complications.

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Key information

Conditions

Gastroesophageal Reflux Disease Barrett Esophagus Deglutition Disorders Digestive System Diseases Esophageal Diseases Esophageal Motility Disorders Esophagitis Gastroenteritis Gastroesophageal Reflux Gastrointestinal Diseases Laryngeal Diseases Laryngopharyngeal Reflux Neoplasms Precancerous Conditions Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

UCI-Irvine, Orange, California, United States

About this study

This registry is a prospective, multicenter registry of patients undergoing diagnostic evaluation and/or treatment of gastroesophageal reflux disease and associated diseases and complications.

Patients who are eligible will have disease and therapy-specific data collected throughout treatment and long-term (5-year) follow-up.

Electronic data capture via REDCap will be utilized for all sites.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Referred GERD patients willing to participate in long term follow-up (5 years)

Exclusion criteria

Potential participants will be excluded if unwilling or unable to complete surveillance questionnaires through this registry

Treatment and study plan

Primary outcomes

Demographic and clinical data obtained via chart review and questionnaires

Time frame: 5 years

Establish a registry with collected data related to patients undergoing diagnostic evaluation and treatment of GERD and its associated diseases in multiple academic and community settings.

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

EndoGastric Solutions

Registry information

Important dates

Study start: 2019
Primary completion: 2026
Study completion: 2027
First posted: Feb 26, 2019
Registry last updated: Dec 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed