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OpenTrials
Completed

NCT Number: NCT00196443

The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Disease

The purpose of this study is to investigate if wearing of compression stockings influences the skin moisture. Conservative stockings are compared with urea containing compression stockings to find out if using urea prevents dehydration of the skin while wearing the urea compression stockings. Secondary aim was to find out if urea containing stockings increase the compliance to wear the compression stockings regulary by patients with diagnosed chronic venous insufficiency.

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Key information

Conditions

Venous Insufficiency Cardiovascular Diseases Vascular Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Clinic and Polyclinic of Dermatology, Ernst-Moritz-Arndt-University of Greifswald

Greifswald, Fleischmannstr. 42-44, 17475, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clincial diagnosis of chronic venous insufficiency
  • Age: 18-80 years
  • Patient's information and willingness to participate

Exclusion criteria

  • Age under 18 years
  • Lower limp edema not caused by venous insufficiency
  • Acute deep venous thrombosis
  • Arterial occlusive disease
  • Diabetes mellitus with neuropathy or peripheral arterial disturbance of perfusion
  • immobile Patients
  • Pregnancy

Treatment and study plan

urea contained compressing stockings

Device

compressing stockings

Device

Primary outcomes

  1. skin moisture at day 0 and day 7

  2. loss of water throughout epidermis at day 0 and day 7

  3. throatiness of epidermis at day 0 and day 7

Secondary outcomes

  1. compliance of patients at every day of intervention

Sponsors and collaborators

Lead sponsor

University Medicine Greifswald

Other

Collaborators

  • Bauerfeind AG, Zeulenroda, Germany

Registry information

Official study title

Prospective, Randomized and Explorative Controlled Study About Influences of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Insufficiency

Important dates

Study start
2005
Study completion
2005
First posted
Sep 20, 2005
Registry last updated
Sep 20, 2005

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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