Black rice
Dietary SupplementThey asked to keep their normal life style during intervention
NCT Number: NCT02407522
The purpose of this study is to thoroughly investigate how the interaction between black rice and human gut microbiota affects metabolic diseases, this study will recruit patients with Metabolic Syndrome (MS) and provide them with dietary supplementation of black rice (50 g/day) for 3 months to observe its effect on the development of MS. The focuses of this project are to elucidate how black rice consumption affects the composition and metabolism of intestinal bacteria as well as the development of MS, and to further analyze whether the changes in intestinal bacteria are associated with the changes in MS improvements.
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Notify Me40 year–80 year
All sexes
Interventional
Phase 2 / Phase 3
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
They asked to keep their normal life style during intervention
They asked not to consume any black rice or excess amount of food rich in anthocyanin compared to their normal life style, such as grapes, blueberry, red wine, black bean during intervention.
Time frame: 3 months
Numerator is number of people is metabolic syndrome at baseline but not after intervention. The denominator is the overall number of people in the group
Time frame: 3months
PCR analysis the RNA of Bacteroides in faeces
Time frame: 3months
PCR analysis the RNA of Bacteroides in faeces
Time frame: 3 months
(after intervention - baseline)/baseline×100%
Time frame: 3 months
(after intervention - baseline)/baseline×100%
Time frame: 3 months
(after intervention - baseline)/baseline×100%
Time frame: 3 months
(after intervention - baseline)/baseline×100%
Time frame: 3 months
(after intervention - baseline)/baseline×100%
Sun Yat-sen University
Other
The Improvements of Dietary Supplement of Black Rice on Metabolic Syndrome and Its Correlation With Metabolism of Gut Microbiota
Acronym: IDSBRMS
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