I-Cheng Lu
Kaohsiung City, 807, Taiwan
Completed
NCT Number: NCT03911232
The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve
Objectives: The use of neuromuscular blocking agent may interfere with the function of intraoperative neuromonitoring (IONM) in thyroid surgery.
Completed
Looking for future studies?
Notify MeKey information
Conditions
Age range
20 year–80 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
An enhanced neuromuscular-blockade (NMB) recovery protocol was investigated in a clinically applied during thyroid neural monitoring surgery. In as subsequent clinical application study, 60 patients who underwent thyroidectomy with IONM followed an enhanced NMB recovery protocol- rocuronium 0.6 mg/kg at anesthesia induction and sugammadex 2 mg/kg at operation start. Train-of-four (TOF) ratio was used for continuous quantitative monitoring of neuromuscular transmission.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- patients undergoing intraoperative neuromonitoring of recurrent laryngeal nerve during thyroidectomy
Exclusion criteria
- Patients with a history of significant cardiac, pulmonary, hepatic, or renal disease, body mass index <18.5 or >35, chronic drug or alcohol abuse
Treatment and study plan
Sugammadex
Drugstandard general anesthesia protocol with sugammadex
Other names: Bridion
Primary outcomes
-
sugammadex 2 mg/kg allows effective and rapid restoration of neuromuscular function suppressed by rocuronium
Time frame: 1 month each case
Electromyography signal to assess the quality of neuromonitoring
Sponsors and collaborators
Lead sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Other
Registry information
Official study title
The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve During Thyroid Surgery
Important dates
- Study start
- 2015
- Primary completion
- 2016
- Study completion
- 2016
- First posted
- Apr 11, 2019
- Registry last updated
- Jun 30, 2021
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.