Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06795815

The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease

This is a mixed-method, device-free and drug-free multicenter interventional study. The study aims at facilitating end-of-life conversations within the doctor-patient relationship through the use of the Go Wish Game (GWG) and supporting patients, their caregivers and healthcare professionals to complete Advance Care Panning documentation.

The GWG helps people clarify and identify their priorities, should they be affected by a chronic, disabling and potentially non-healing illness. In fact, the GWG consists of a small deck of cards, and on each card is a concrete action or situation that may be important to a person at the end of life.

The "Onco-hema Go wish-ACP" project aims to evaluate the feasibility of a Go Wish Game-based intervention with patients with refractory lymphoma, leukemia or multiple myeloma or advanced solid tumors with prognosis > 3 months.

In terms of secondary objectives, the study aims to.

* Evaluate and compare the intervention with hematology and oncology patients in terms of: - Other feasibility indicators; Involvement in CCP pathways; Quality of communication; Meaning of life; Impact on hope; through a series of questionnaires administered to patients and caregivers involved in the intervention * Qualitatively assess the acceptability of the intervention in terms of recruitment and delivery with patients and caregivers through semi-structured interviews and with professionals through Focus Groups (FGs). * To analyze the clinical records of enrolled patients in terms of: values and preferences; awareness of prognosis; end-of-life choices and shared decision-making on treatment decisions.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Leukemia Advanced Solid Tumors Hematologic Diseases Hemic and Lymphatic Diseases Immune System Diseases Immunoproliferative Disorders Lymphatic Diseases Lymphoma Lymphoproliferative Disorders Multiple Mieloma Neoplasms Neoplasms by Histologic Type Oncology

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

AziendaUSL IRCCS Reggio Emilia

Reggio Emilia, Italy

Location status: Recruiting

Location contact

Marta Perin

CONTACT

[email protected]

3463576133

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ≥ 18 years age; diagnosed with refractory lymphomas, or leukemia or multiple myeloma or advanced solid tumors and estimated prognosis > 3 months;
  • able to communicate in Italian and
  • to give written consent to the study.

Exclusion criteria

  • Patients with severe cognitive impairment or serious psychiatric condition;
  • refusal to participate to the study

Treatment and study plan

Go Wish Game

Other

The Go Wish Game (GWG) provides a simple tool, composed by 35 cards to identify individual priorities. GWG is welcomed as a first step in clarifying values and personal thoughts linked to the end of life. The GWG discussion will be divided into two meetings. During the first one, the physician instructs the patients and their caregivers on how the GWG works. The patient will be invited to divide the cards into three sets, labeling the content of the cards within each set as: Very important;more or less important and not important.

This will be the base for the second meeting. During the second meeting - scheduled within one week - each category of card sets will be discussed with patients and their caregivers. The identification of the most relevant wishes or priorities of each patient will be incorporated into the individual therapeutic plan and the patient will be offered the option to make a formal ACP in the following 4 weeks.

Primary outcomes

  1. Intervention Feasibility

    Time frame: 1 Year

    We will evaluate the feasibility of the intervention. Feasibility will be investigated by:

    • proportion of patients who will accept to participate among those screened/eligible who received the proposal to participate;
    • proportion of enrolled patients who will withdraw from the study after the first GWG discussion among the enrolled patients; 3, percentage proportion of enrolled patients who will attend all the planned GWG discussions;
    • proportion of enrolled patients that will complete the ACP document (after participating in all the planned GWG discussions)

Secondary outcomes

  1. ACP Engagement;

    Time frame: 18 Months

    We will further assess and compare the intervention within hemato-oncological and oncological patients in terms of:

    • ACP engagement: we will use the 4-item ACP Engagement (4-item ACP-E) questionnaire

  2. Quality of Communication;

    Time frame: 18 Months

    We will further assess and compare the intervention within hemato-oncological and oncological patients in terms of:

    • Quality of communication: we will use the 19-item Quality of Communication (QOC) questionnaire

  3. Meaning of Life;

    Time frame: 18 Months

    We will further assess and compare the intervention within hemato-oncological and oncological patients in terms of:

    • Meaning of life: we will use the Meaning in Life scale (MLS)

  4. Impact on patients' hope

    Time frame: 18 Months

    We will further assess and compare the intervention within hemato-oncological and oncological patients in terms of:

    • Impact on patients' hope: we will use the Hope Herth Index (HHI)

  5. Acceptability

    Time frame: 18 Months

    • Acceptability of intervention in terms of recruitment and intervention delivery will be further investigated by: semi-structured interviews with patients and caregivers and FG with HPs who applied the GWG.

    .

  6. ACP documentation

    Time frame: 18 Months

    We will analyze the ACP documentation of patients enrolled to qualitatively investigate the congruence and relations between the priorities defined during the GWG meetings and the decisions written in the care plan

Study contacts

Contact information is provided by the study sponsor or research team.

Andrea Fusco, MSc

CONTACT

[email protected]

+39 3409136595

Marta Perin (Dr), PhD

CONTACT

[email protected]

+39 3463576133

Sponsors and collaborators

Lead sponsor

Azienda USL Reggio Emilia - IRCCS

Other Gov

Registry information

Official study title

The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco-hematologic Disease (Onco-hema Go Wish-ACP): Intervention Set up and Multicentre Feasibility Trial

Acronym: OHGW-ACP

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 28, 2025
Registry last updated
May 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.