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NCT Number: NCT06559852

The Impact of Yoga on Endometriosis-Related Pain

The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.

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Key information

Conditions

Endometriosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Pelvic Pain Signs and Symptoms Urogenital Diseases

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Penn State Health

Hershey, Pennsylvania, 17033, United States

Location status: Recruiting

Location contact

Ashlie Carter, MD

CONTACT

[email protected]

7175313503

About this study

Yoga has been demonstrated to improve menstrual pain associated with primary dysmenorrhea through use of physical exercises, mental meditation, and breathing techniques. Still, there has been limited studies assessing potential benefits of yoga on pain symptoms of endometriosis. It is important to further assess yoga as a complementary therapy for women with endometriosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Reproductive aged women 18-45
  • Self-reported prior surgery with pathology confirming a diagnosis of endometriosis
  • No current use of yoga
  • Baseline moderate pain, score greater than or equal to 5 on VAS scoring
  • Access to internet with wifi capability for zoom platform and completion of weekly surveys
  • Access to items required for yoga session participation (2 blankets or towels, firm pillow, stable chair, wall space, comfortable clothing, water)
  • Ability to commit to duration of 12-week yoga course

Exclusion criteria

  • Pregnant patients
  • Established yoga participation or moderate exercise regimen
  • Physical trauma or disability
  • Planned surgery or hormonal medication change during study
  • Non-English speaking patients

Treatment and study plan

Yoga

Behavioral

Participants will engage in a 12-week virtual yoga course to assess impact on endometriosis-related pain

Primary outcomes

  1. Change in Endometriosis Health Profile-30 Pain Score

    Time frame: Baseline to completion at 12-weeks

    Identify the impact of yoga on endometriosis related pain based on the Endometriosis Health Profile-30, with specific focus on the domain of pain. The EHP-30 questionnaire consists of five scales which includes pain, control and powerlessness, emotional well-being, social support, and self-image and a total of 30 questions. Each scale is translated into a score ranging from 0, or the best health status, to 100, the worst health status.

Secondary outcomes

  1. Change in Visual Analog Scale scores

    Time frame: Baseline to completion at 12-weeks

    Comparison of visual analog scale scores from start to the end of the study. The visual analog scale is a validated scale for measuring acute and chronic pain. Scores are recorded on a scale between 0 or "no pain" and 10, the "worst pain".

Study contacts

Contact information is provided by the study sponsor or research team.

Ashlie Carter, MD

CONTACT

[email protected]

7175313503

Linda Li, MD

CONTACT

[email protected]

7175313503

Sponsors and collaborators

Lead sponsor

Milton S. Hershey Medical Center

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 19, 2024
Registry last updated
May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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